Chicago’s Life Sciences Sector Hits A Wall — Again  
   
   
 

Chicago’s life sciences market has posted vacancy numbers showing it is far weaker than its next closest major markets, with about 4 in 10 spaces sitting empty, according to new CBRE data.

 
 
Pexels/Chokniti Khongchum
 
   
 

The glut of available space was born out of developers rushing into the market when available properties were limited at the onset of the pandemic, combined with a tough capital market that has made it tricky for tenants to sign leases, life sciences insiders told Bisnow

The vacancy rate for Chicago’s life sciences sector was 40.5% as of the fourth quarter of 2024, with about 2M SF of total inventory, according to CBRE’s Q4 national life sciences report. The next closest metro areas were the San Francisco Bay Area at 28.7% and Houston at 23.4%. 

Read more about the embattled sector here.

— Ryan Wangman

 
 

Today's Rundown

 
 

Willis Tower Loan Extended: Blackstone extended the maturity date on its $1.3B Willis Tower loan by three years, according to reports. The Willis Tower loan also made a brief stop in special servicing ahead of its previous March 2025 maturity. Read more

With Retail Pharmacies Under The Weather, CRE Grapples For The Right Prescription: Hundreds of pharmacies are closing, and that's bringing headaches and opportunities to their landlords. Filling the spaces isn't an issue, but some owners are having to settle for lower-quality tenants. Read more

Prologis CEO Hamid Moghadam To Retire: Moghadam will step down effective Jan. 1, 2026, and will be succeeded by Prologis President Dan Letter, who has been at the company for two decades. Read more.

 
 

What Else Is Happening?

 
 
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The Finish Line

 
 

An environmental nonprofit is looking for help naming what it calls a “remarkably rotund” and likely pregnant beaver eating and knocking down trees on the Southwest Side. Monikers in the mix include: Lori Heavyfoot, Southside Large Marge, Dam Ryan, Sufjan Beavens and Sigourney Beaver. Do you have a CRE-centered name for the spherical beaver? Let us know.

The Chicago Rundown is written by Chicago Reporter Ryan Wangman and edited by Central Editor Katharine Carlon. If you enjoyed today’s edition, please share and forward with anyone you think might find it interesting. We’d also love your feedback and news tips: ryan.wangman@bisnow.com.

 
   
 
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